It’s easy to see why Barcelona is the most-visited city in Spain. As the capital of the country’s Catalonia region, this cityscape’s cultural mosaic pieces together a 2,000-year-old hodge-podge of sun-drenched beaches, cutting edge architecture and a world-renowned dining and drinking scene. Catalan architect Antoni Gaudi left his modernist handprint all over the city, while medieval treasures linger in historic Gothic Quarter squares. Get lost in the whimsical gardens of Park Guell or savour a chef-led Catalan cooking class. Browse art collections dedicated to Picasso and Miro – or ride a cable car to the top of Montjuic Hill, relishing citywide views along the way.

Spain’s third largest city, Valencia offers a little bit of everything, from historic sites and bustling city squares to placid beaches. Soak up the sun at Malvarrosa Beach along the urban seafront, or head to El Saler for a more remote beach experience surrounded by white-sand dunes and pine trees. Cruise to Valencia and get your culture fix at Gothic Valencia Cathedral, and see the 15th-century renaissance paintings housed in its interior. Head to Plaza de la Reina in the city’s old town and do some people-watching over a fresh glass of horchata, a classic Valencia beverage made from almond milk with cinnamon and spices, or take a picnic lunch of fresh pears and local cheese to the quiet Turia Gardens.

Cobbled streets, balconies with blooming bougainvillea, and pastel plazas make Cartagena one of Latin America’s most photogenic cities. But it’s not just another pretty seaport. Founded in 1533, this Spanish colonial city is steeped in history. Its location made it a popular port for plunderers and pirates. Today thrill-seekers will find a perfect mix of old and new with a twist of island attitude.

As the capital of Spain’s Andalusia region, the energetic city of Seville stands tall at the banks of the Guadalquivir River. And like its rich flamenco legacy, this well-preserved city performs an elaborate dance between Moorish history and youth-infused street culture. A jovial spirit and intoxicating personality flow freely throughout its narrow streets, from Old Town’s palaces to the tapas bars of Santa Cruz. Admire the lavish stylings of Plaza de España from a painted ceramic bench, or stroll through Maria Luisa Park’s serene greenery. Stand in Spain’s oldest bullring at the Bullfighting Museum – or breathe in citywide views from the top of Torre del Oro.

Tangier, a Moroccan port on the Strait of Gibraltar, has been a strategic gateway between Africa and Europe since Phoenician times. Its whitewashed hillside medina is home to the Dar el Makhzen, a palace of the sultans that’s now a museum of Moroccan artifacts. The American Legation Museum, also in the medina, documents early diplomatic relations between the U.S. and Morocco in an 1821 Moorish-style former consulate

Moroccan mystique envelops this cosmopolitan city, which is considered to be the economic capital of Morocco. Traits of ancient times co-exist with a modern metropolis, and the mix of European, Art-Deco and Art-Nouveau architecture brings colour and vibrancy to the city. Influenced by Arabia and Africa, it is culturally diverse, to say the least, and the exotic sights and smells omitted from the Souk markets are fascinating. Casablanca is awash with white buildings, striking a contrast to the blue Atlantic waters surrounding it, and boasts a thriving city centre and busy boulevards, making it a popular port of call.

Puerto Rico’s 500-year-old capital is a history buff’s dream come true. The Spanish settled this harbour as a New World home base, and that influence is still evident, from the fortress walls lining the coastline to the rainbow of colonial buildings along narrow streets. Venture further out from the old town and nature unfolds. You can scale high into the jungled mountains of El Yunque Forest, or keep to the foothills on a riverside horse ride. If despacito is more your speed, pick a pristine beach and recline with a cod fritter and rum drink in hand. San Juan cruises give you the perfect outpost to dial up or dial down your holiday.