Formerly a sleepy Spanish city, Barcelona has recently been reborn as an eclectic fusion of the modern and medieval. Seek inspiration from the creations of its modernist architect, Antonio Gaudí, or the Picasso Museum. Or, take in the breathtaking cathedrals in the Gothic Quarter.

Civitavecchia was settled in 108 A.D. by the Emperor Trajan and has since served faithfully as a gateway to the capital of the Empire—Rome. Once the center of the Ancient World from which emperors ruled over nearly all of western civilization, Rome is still a cultural mecca. Stroll the ancient halls of the Colosseum or gaze upon the ceilings of the Sistine Chapel.

Naples is a large port city located in southwest Italy and is the capital of Italy’s Campania region. A Naples cruise port of call is an excellent way to visit Italy’s third largest city and experience everything this famous city is known for, including pizza, history, and it’s close proximity to several of Italy’s most famous places.

Due to its location, Naples is a unique port city for travelers on Mediterranean cruises. It has the allure of an energetic city since Naples is home to a vibrant historic center and famous culinary scene, but it is also the gateway to some of the most alluring places in the world. The Amalfi Coast, the island of Capri, and the lost city of Pompeii are all an easy day trip away.

Located in northeastern Sicily, on the slopes of the Peloritani Mountains, Messina is an ancient place with a fascinating history. Walk by the ruins of the Santa Maria Alemanna church, built in 1220 by the Teutonic Knights. You’ll also want to see the Duomo, a Romanesque and Norman cathedral that includes a display of artifacts in its treasury

Nestled along the craggy shores of the Aegean Sea is the Turkish port of Kusadasi. Renowned as one of the most beautiful cities along the Aegean, Kusadasi is blessed with sunshine an average of 300 days a year. This beautiful city is the perfect setting to begin your journey to Ephesus.

Like many ports in this part of the world, archeological ruins dating back to antiquity are found everywhere. There are also hundreds of gorges around the island and over 1,500 land and sea caves, including Elefantos, noted for its remarkable white and red stalactites.

Your adventure in Athens begins five miles southwest in Greece’s largest seaport, known as Piraeus. While here, be sure to take notice of what is considered to be one of the greatest contributions from the ancient Age of Pericles, the city’s infrastructure, which today we know as a city block.